Calcitriol and energy metabolism
نویسندگان
چکیده
منابع مشابه
Calcitriol and energy metabolism.
Calcitriol, a calcitrophic hormone that can be suppressed by high dietary calcium, favors fatty acid synthesis and inhibits lipolysis via non-genomic modulation of Ca(2+) influx. Calcitriol also suppresses UCP2 expression via the nVDR and thereby increases energy efficiency. Calcitriol exerts a dose-dependent impact on adipocyte apoptosis and regulates adipose tissue fat depot location and expa...
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Abnormalities of calcium metabolism and of its two principal regulating hormones, parathyroid hormone and 1,25-dihydroxyvitamin D3 (calcitriol), have been reported in the spontaneously hypertensive rat (SHR). Reports of abnormal calcitriol metabolism in the SHR by several groups have not provided measurements of tissue calcitriol receptors. Similarly, few data are available as to the parathyroi...
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Over the long-term, most adult humans are able to maintain body energy stores through the process of energy balance, which regulates how much energy is consumed to match how much energy is expended. Energy expenditure is required for resting metabolic rate to maintain basic physiologic functions (e.g., heart beat, muscle function, respiration) and metabolize, digest, and store food that is cons...
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Sirtuin 1 (SIRT1) is the most conserved mammalian NAD(+)-dependent protein deacetylase that has emerged as a key metabolic sensor in various metabolic tissues. In response to different environmental stimuli, SIRT1 directly links the cellular metabolic status to the chromatin structure and the regulation of gene expression, thereby modulating a variety of cellular processes such as energy metabo...
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A wide range of adipokines identified over the past years has allowed considering the white adipose tissue as a secretory organ closely integrated into overall physiological and metabolic control. Apelin, a ubiquitously expressed peptide was known to exert different physiological effects mainly on the cardiovascular system and the regulation of fluid homeostasis prior to its characterization as...
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ژورنال
عنوان ژورنال: Nutrition Reviews
سال: 2008
ISSN: 0029-6643
DOI: 10.1111/j.1753-4887.2008.00099.x